genotype
genetic makeup
the genes or versions of genes that a living thing has
the genotype of [an organism/cell/individual]; [someone/something]'s genotype; genotype for [a gene/trait]
- A person's genotype can affect how they respond to certain medicines.
- Identical twins usually have the same genotype, although their experiences and health can differ.
- The plant's drought tolerance depended partly on its genotype.
- The child's genotype is inherited from both parents.
- Genotype is about genes, not appearance.
genetically distinct variant
one genetic type of a virus, plant, animal, or other living thing
[a virus/species/pathogen] genotype; genotype [number/letter]
- Some hepatitis C genotypes respond differently to treatment.
- Scientists found three genotypes of the parasite in the samples.
- The vaccine was tested against several viral genotypes.
- The virus has many genotypes.
- This genotype is common in the region.
identify genetic makeup
to test DNA to find which genes or gene versions something has
genotype [someone/something]; genotype [a sample/population] for [a variant/marker]
- The team genotyped 2,000 volunteers to study risk factors for the disease.
- All tumor samples were genotyped for two common mutations.
- Farmers can genotype seedlings before choosing which plants to grow.
- The lab genotyped the samples.
- Doctors may genotype a virus before treatment.
- Base: genotype
- Plural: genotypes
- Base: genotype
- 3rd Person Singular: genotypes
- Present Participle: genotyping
- Past: genotyped
- Past Participle: genotyped
genotype frequency
1rate of a genotype
how common a particular genotype is in a group
- Genotype frequencies differed between the patient group and the control group.
- The rare genotype had a frequency of less than 2 percent in the sample.
- Researchers compared genotype frequencies across several regions.
genotype-environment interaction
1genes depend on environment
when genes and environment affect each other in producing a trait
- The study reported a genotype-environment interaction: one crop variety produced high yields only under irrigation.
- Genotype-environment interaction is a major concern when breeders test plants in different climates.
- The researchers found a genotype-environment interaction for weight gain in the animal model.
genotype-phenotype correlation
1gene-trait relationship
a link between genes and visible traits or medical features
- A clear genotype-phenotype correlation can help doctors predict disease severity.
- Researchers looked for genotype-phenotype correlations in patients with the same inherited disorder.
- The mutation showed a strong genotype-phenotype correlation in the study population.
genotype-phenotype correlation
1gene-trait relationship
a link between someone's genes and the traits or symptoms they show.
- The database helps researchers study genotype-phenotype correlations in inherited heart disease.
- A strong genotype-phenotype correlation can make it easier to predict how severe a condition will be.
- The variant is common, but its genotype-phenotype correlation is still unclear.
mutant genotype
1genotype with mutation
a genetic form that has the mutation being studied
- Larvae with the mutant genotype failed to develop normally.
- The assay clearly separated the wild-type genotype from the mutant genotype.
- Researchers studied how the mutant genotype affected enzyme activity.
sickle-cell genotype
1hemoglobin gene category
a genetic result showing whether a person has sickle-cell trait or sickle-cell disease
- Newborn screening can identify a baby's sickle-cell genotype.
- Couples in some regions are encouraged to learn their sickle-cell genotypes before having children.
- The report listed her sickle-cell genotype as AS.
wild-type genotype
1reference non-mutant genotype
the usual or reference genetic form used for comparison
- The control mice carried the wild-type genotype.
- The experiment compared mutant plants with plants that had the wild-type genotype.
- Cells with the wild-type genotype responded normally to the drug.